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Lowest round trip fares by airline from Indianapolis and Rome

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fly From Indianapolis to Rome

OriginIndianapolis
DestinationRome
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Cheap flights from Indianapolis to Rome

Cheap flights from Indianapolis to Rome

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Rome Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Rome vacation that you can't get when you book flights and hotel separately.

Relax in Rome With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

Need to grab a cheap travel deal while you're on the go? Download our mobile app, where you can search and book just like you would on your home computer. Stay in-the-know on great rates on flights from Indianapolis to Rome by signing up for exclusive email deals.

Hotels in Rome

See all 11,277 Properties in Rome
Hotel Quirinale

Hotel Quirinale

Via Nazionale 7, Rome, RM
    4.0 out of 5.0
     
     
    4.8 out of 5 (4 reviews)

    Located in Repubblica, this family-friendly Rome hotel is steps from Teatro dell'Opera di Roma, Via Nazionale, and Via XX Settembre. Via Veneto and Basilica ...

    Hotel Quirinale$85

    Hotel Quirinale$85
    NH Collection Roma Palazzo Cinquecento

    NH Collection Roma Palazzo Cinquecento

    Piazza Dei Cinquecento, 90, Rome
      5.0 out of 5.0
       
       
      4.7 out of 5 (3 reviews)

      Located in Esquilino, this hotel is 2.1 mi (3.3 km) from Circus Maximus. Rome Termini Station is only a 3-minute walk and Repubblica - Opera House Station is ...

      NH Collection Roma Palazzo Cinquecento$171

      NH Collection Roma Palazzo Cinquecento$171
      Best Western Plus Hotel Universo

      Best Western Plus Hotel Universo

      Via Principe Amedeo 5/B, Rome, RM
        4.0 out of 5.0
         
         
        4.0 out of 5 (6 reviews)

        Located in Rome City Centre, this hotel is within a 10-minute walk of Baths of Diocletian, Basilica di Santa Maria Maggiore, and Palace of Expositions. Repubblica ...

        Best Western Plus Hotel Universo$79

        Best Western Plus Hotel Universo$79
        Hotel Artemide

        Hotel Artemide

        Via Nazionale 22, Rome, RM
          4.0 out of 5.0
           
           
          4.4 out of 5 (5 reviews)

          Located in Repubblica, this spa hotel is within a 15-minute walk of Baths of Diocletian, Trevi Fountain, and Spanish Steps. Roman Forum and Villa Borghese are ...

          Hotel Artemide$137

          Hotel Artemide$137
          Hilton Rome Airport

          Hilton Rome Airport

          Via Arturo Ferrarin 2, Fiumicino, RM
            4.0 out of 5.0
             
             
            3.8 out of 5 (13 reviews)

            Situated near the airport, this hotel is 2.7 mi (4.4 km) from Necropoli di Porto Isola Sacra and within 6 mi (10 km) of Ostia Antica and Parco Leonardo. Area ...

            Hilton Rome Airport$156

            Hilton Rome Airport$156
            iQ Hotel Roma

            iQ Hotel Roma

            Via Firenze, 8, Rome, RM
              4.0 out of 5.0
               
               
              4.8 out of 5 (10 reviews)

              Located in Repubblica, this hotel is steps from Teatro dell'Opera di Roma and Via Nazionale. Via XX Settembre and Piazza della Repubblica are also within 5 minutes. ...

              iQ Hotel Roma$78

              iQ Hotel Roma$78
              UNAHOTELS Decò Roma

              UNAHOTELS Decò Roma

              Via Giovanni Amendola, 57, Rome, RM
                4.0 out of 5.0
                 
                 
                4.3 out of 5 (7 reviews)

                Located in Rome City Centre, this hotel is within a 10-minute walk of Via Nazionale, Teatro dell'Opera di Roma, and Basilica di Santa Maria Maggiore. Piazza ...

                UNAHOTELS Decò Roma$119

                UNAHOTELS Decò Roma$119
                Hotel Raffaello

                Hotel Raffaello

                Via Urbana 3/5, Rome, RM
                  3.0 out of 5.0
                   
                   
                  5.0 out of 5 (1 reviews)

                  Located in Monti, this hotel is within a 5-minute walk of Basilica di Santa Maria Maggiore and Teatro dell'Opera di Roma. Via Nazionale and Via XX Settembre ...

                  Hotel Raffaello$57

                  Hotel Raffaello$57
                  Hotel Condotti

                  Hotel Condotti

                  Via Mario Dè Fiori 37, Rome, RM
                    4.0 out of 5.0
                     
                     

                    This family-friendly Rome hotel is located in the historical district, steps from Via Condotti, Piazza di Spagna, and Via del Corso. Spanish Steps and Pincio ...

                    Hotel Condotti$68

                    Hotel Condotti$68
                    Best Western Hotel Rome Airport

                    Best Western Hotel Rome Airport

                    Via Portuense, 2465, Fiumicino, RM
                      4.0 out of 5.0
                       
                       
                      3.3 out of 5 (3 reviews)

                      Situated near the airport, this hotel is 1.7 mi (2.7 km) from Necropoli di Porto Isola Sacra and 1.7 mi (2.8 km) from Area Archeologica del Porto di Traiano. ...

                      Best Western Hotel Rome Airport$61

                      Best Western Hotel Rome Airport$61
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.