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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property class: 2.5

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Free WiFi
  • Air conditioning
The current price is $131
$114 nightly
$131 total
Total with taxes and fees
Oct 25 - Oct 26

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Gateway Arch
    ‪17 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Place, St. Louis Zoo
    ‪23 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.6 out of 10
Exceptional
(14 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.6 out of 10
Exceptional
(35 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free wired internet

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.2 out of 10
Wonderful
(5 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(18 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

Standard Room

  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bed
  • Free wired internet

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free wired internet

View all photos for Standard Room, 2 Queen Beds

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(84 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

Similar properties

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.
Hampton Inn & Suites St. Louis/South I-55
St. Louis
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.8 out of 5, Exceptional, 1,000 reviews
$110 nightly
The price is $126
Oct 30 - Oct 31
Total with taxes and fees
Hampton Inn & Suites St. Louis/South I-55

About the neighborhood

St. Louis

Located in St. Louis, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is in the business district, within a 5-minute drive of Barnes Jewish South Campus and BounceU of St. Louis. .This hotel is 13.4 mi (21.5 km) from St. Louis Zoo and 11.3 mi (18.2 km) from Missouri Botanical Garden.

What's nearby

  • Busch Stadium - 16 min drive - 17.6 miles
  • Gateway Arch - 17 min drive - 18.0 miles
  • Enterprise Center - 17 min drive - 18.2 miles
  • St. Louis Union Station - 18 min drive - 17.6 miles
  • St. Louis Zoo - 23 min drive - 22.2 miles

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪McDonald's - ‬4 min drive
  • ‪Burger King - ‬11 min walk
  • ‪Hardee's / Red Burrito - ‬11 min walk
  • ‪Subway - ‬3 min drive
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with safes and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
Make yourself at home in one of the 99 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Be sure to enjoy recreational amenities including an indoor pool and a 24-hour fitness center. Additional features at this hotel include complimentary wireless internet access, a banquet hall, and a vending machine.
A complimentary buffet breakfast is served daily from 6:00 AM to 9:30 AM.
Featured amenities include a business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite.
A complimentary buffet breakfast is served each morning between 6:00 AM and 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Property payment types

  • American Express
  • Diners Club
  • Discover
  • JCB International
  • Mastercard
  • Visa

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 793 out of 1000 reviews
Rating 8 - Good. 145 out of 1000 reviews
Rating 6 - Okay. 39 out of 1000 reviews
Rating 4 - Poor. 15 out of 1000 reviews
Rating 2 - Terrible. 8 out of 1000 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice stay with polite and helpful staff.
Stayed 4 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff were friendly, hotel was super quiet, room was immaculately clean! Will definitely stay here again!
Stayed 1 night in May 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stay here often, never have a issue
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was wonderful and the accommodations were cleani, quiet and just what I needed.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I definitely would recommend this hotel to stay at. The property and rooms were VERY CLEAN. The breakfast was delicious and the very good coffee as well.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was amazing - they went out of their way to ensure our stay was great
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and comfortable. Staff was great 👍
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was excellent!!
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Great stay
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything we needed plus a cookie hour with free milk and cookies
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great facility with very friendly and accommodating staff!
Stayed 4 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy to find, super helpful staff, room was clean and quiet. We agreed we would absolutely stay there again. Very accessible for two elderly women with mobility and vision issues and the beds were surprisingly comfortable. Their breakfast was also a very nice perk, the food was better than we expected!
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean people very nice
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Overnight Mother's Day trip was a great stay at the Holiday Inn Express I55 South location. Normally would lodge at Hampton Inn next door when I visited St. Louis but definitely found better at Holiday Inn express. Staff was very nice and breakfast was a big winner with Bacon 😉
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was good
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities
Clean rooms, great friendly staff, very good breakfast with lots to choose from
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Desk staff was very friendly, room was nice and clean, kids loved the pool, breakfast was great!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service
Clean room, friendly staff.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Best hotel we have stayed in a long time! Quiet, clean, smoke and pet free rooms. We have nothing against pets but would like to stay in a room where a pet has not slept in/on the beds. Breakfast area clean and the food was good. Close to the highway allowing easy access off/on. Highly recommend and would stay here again!
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, location was ideal for activities in St Louis, complimentary parking and warm cookies at night!
Stayed 4 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brand new hotel great beds and quiet despite it being sold out the night we stayed.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was one of our favorite hotels we have ever stayed at. We really don’t have any complaints. Everything was clean and everyone was nice. Breakfast was good. Coffee was excellent.
Stayed 3 nights in May 2026
Verified review

6/10 Okay

Liked: Staff & service
The staff at the front desk were great. I don’t feel like the room was as clean at it normally is when we stay there every summer. One of the beds had something on the comforter (looked like chocolate) so I’m not sure the sheets were clean.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good breakfast selection, clean room. Overall clean place. Friendly and helpful staff. Pool is a little small so keep that in mind when traveling with kids, but it was a nice pool!
Stayed 3 nights in May 2026
Verified review

10/10 Excellent

Clean room, location, excellent staff
Stayed 4 nights in Dec 2025