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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenity
Free daily buffet breakfast
Fitness facility
Property amenity
Exterior

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning
$136
$118 nightly
$136 total
Total with taxes and fees
May 10 - May 11

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Barnes Jewish South Campus
    ‪6 min walk‬
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout drapes

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.4 out of 10
Exceptional
(30 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.0 out of 10
Wonderful
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(17 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room

Standard Room | In-room safe, desk, laptop workspace, blackout drapes

Standard Room

  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(75 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

Similar properties

Lobby
Hampton Inn & Suites St. Louis/South I-55
St. Louis
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.8 out of 5, Exceptional, 1,002 reviews
$137 nightly
The price is $158
May 3 - May 4
Total with taxes and fees
Hampton Inn & Suites St. Louis/South I-55

About the neighborhood

St. Louis

Located in St. Louis, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is in the business district, within a 5-minute drive of Barnes Jewish South Campus and BounceU of St. Louis. .This hotel is 12.4 mi (20 km) from Forest Park and 13.4 mi (21.5 km) from St. Louis Zoo.

What's nearby

  • Barnes Jewish South Campus - 6 min walk - 0.4 miles
  • Busch Stadium - 16 min drive - 17.6 miles
  • Gateway Arch - 17 min drive - 18.0 miles
  • St. Louis Union Station - 18 min drive - 17.6 miles
  • St. Louis Zoo - 23 min drive - 22.2 miles

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪McDonald's - ‬5 min drive
  • ‪Burger King - ‬10 min walk
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Hardee's / Red Burrito - ‬11 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with safes and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
Make yourself at home in one of the 99 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Be sure to enjoy recreational amenities including an indoor pool and a 24-hour fitness center. Additional features at this hotel include complimentary wireless internet access, a banquet hall, and a vending machine.
A complimentary buffet breakfast is served daily from 6:00 AM to 9:30 AM.
Featured amenities include a business center, a 24-hour front desk, and a safe deposit box at the front desk. Free self parking is available onsite.
A complimentary buffet breakfast is served each morning between 6:00 AM and 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 799 out of 1000 reviews
Rating 8 - Good. 144 out of 1000 reviews
Rating 6 - Okay. 35 out of 1000 reviews
Rating 4 - Poor. 15 out of 1000 reviews
Rating 2 - Terrible. 7 out of 1000 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Ashley, Bloomfield

Stayed 1 night in Jan 2026

10/10 Excellent

Tonya

Business traveler
Liked: Cleanliness, staff & service, amenities
Clean room, facility, exceptional continental breakfast. One issue was heat or air not working. They promptly got me a new room. Kind and courteous service. I would definitely stay here again.
Stayed 1 night in Jan 2026

8/10 Good

Alyssa

Liked: Cleanliness, amenities, property conditions & facilities
Cookies and milk at night was a nice touch, the breakfast was pretty decent and the room was clean. My only complaint was having a room on the main level, as I could easily hear the people outside/walking by the room window.
Stayed 1 night in Jan 2026

8/10 Good

Eleanor

Traveled with family
Liked: Cleanliness, staff & service, amenities
Everything was clean. Coffee was great. Breakfast was better than expected. We will be staying at this hotel our next trip to St. Louis.
Stayed 2 nights in Jan 2026

10/10 Excellent

Aneta

Liked: Cleanliness, staff & service, amenities
Yes
Stayed 1 night in Jan 2026

10/10 Excellent

Jennifer

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Everything was very clean. Breakfast was good. And coffee in the lobby was really appreciated. It has been a long time since I have stayed at a Holiday Inn Express but I'd definitely stay here again.
Stayed 1 night in Jan 2026

10/10 Excellent

Arielle

Stayed 1 night in Jan 2026

10/10 Excellent

Pamela

Liked: Cleanliness, amenities, property conditions & facilities
Staff is very nice! The rooms are clean and comfortable.
Stayed 1 night in Jan 2026

8/10 Good

Tracy

Stayed 1 night in Jan 2026

8/10 Good

Shilouh, Chester

Stayed 2 nights in Oct 2025

10/10 Excellent

Brandy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Friendly staff clean rooms
Stayed 1 night in Jan 2026

10/10 Excellent

Kevin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Had to make a 2 day trip to Wisconsin from Texas. As always we stayed at Holiday inn because we know we will get a nice clean place to stay with a good breakfast. Also we feel safe staying at your Hotels. Thanks to your staff, we had a worry free trip.
Stayed 2 nights in Jan 2026

10/10 Excellent

Christopher

Stayed 1 night in Jan 2026

10/10 Excellent

Mary

Stayed 5 nights in Dec 2025

10/10 Excellent

Anita

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean and staff was friendly.
Stayed 2 nights in Nov 2025

10/10 Excellent

James

Traveled with family
Clean room, location, excellent staff
Stayed 4 nights in Dec 2025

10/10 Excellent

Zackariah

Traveled with family and small children
Liked: Cleanliness, amenities, property conditions & facilities
The breakfast was very great! They also served cookies and milk during the evening in the lobby. The gym and swimming pool were very nice and conveniently located near the elevators and outside doorway with two bathrooms nearby.
Stayed 1 night in Dec 2025

10/10 Excellent

Arielle

Business traveler, Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Room was absolutely perfect…. Great space and very clean
Stayed 1 night in Dec 2025

10/10 Excellent

Edwin

Stayed 1 night in Dec 2025

8/10 Good

Therese

Liked: Cleanliness, staff & service, amenities
Clean rooms. Easy check-in. Great breakfast.
Stayed 4 nights in Dec 2025

10/10 Excellent

Walt

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Easy to get there from the highway exit.
Stayed 1 night in Dec 2025

10/10 Excellent

Debra

Stayed 2 nights in Dec 2025

10/10 Excellent

Rock

Stayed 2 nights in Nov 2025

10/10 Excellent

Samantha

Stayed 1 night in Dec 2025

8/10 Good

Jeffrey

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 4 nights in Dec 2025