Southwest Middlesex Vacation Rentals

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Vacation Rentals in Southwest Middlesex

Luxury 5BR· Chef's Kitchen · Sleeps 10 · Premier Host

London ON

With a stay at this vacation home in London, you'll be next to a golf course, within a 15-minute drive of University of Western Ontario and Springbank Park.

My Mom's Cottage - Enjoy Small Town Beach Living!

Port Stanley ON

With a stay at this vacation home in Port Stanley, you'll be within a 10-minute walk of Lake Erie and Port Stanley Terminal Rail.

Modern 4BR/Near Western&Masonville • Prime London

London ON

With a stay at this vacation home in London, you'll be within a 5-minute drive of University of Western Ontario and Museum of Ontario Archaeology.

Relaxing Home Kokomo Beach Area, Sleeps 12, Pet-Friendly, Near Beach & Downtown

Port Stanley ON

With a stay at this vacation home in Port Stanley, you'll be within a 15-minute walk of Lake Erie and Port Stanley Terminal Rail.

Relax house a few minutes from Port Stanley beach, with hot tub and game room

Port Stanley ON

With a stay at this vacation home in Port Stanley, you'll be within a 5-minute drive of Lake Erie and Port Stanley Terminal Rail.

Spacious Pool House – 5 Minutes to Elgin Centre

St. Thomas ON

With a stay at this vacation home in Saint Thomas, you'll be within a 5-minute drive of Galaxy Cinemas St. Thomas and Pinafore Park.

Comfortable Lux | Sleeps 10 | PingPong, Cozy Family Movie Room

London ON

$308 nightly

$348 total

May 4 - May 5

Total with taxes and fees

With a stay at this vacation home in London, you'll be within a 10-minute drive of University of Western Ontario and Bellamere Winery and Event Centre.

Winter Rental; Birders' Joy ; Lake Erie Beach Front; Walkers beach; 3 BR/2 Bath

Morpeth ON

$291 nightly

$328 total

May 1 - May 2

Total with taxes and fees

With a stay at this vacation home in Chatham-Kent, you'll be steps from Lake Erie and Rose Beach Park.

Relax and enjoy your home away from home.

Strathroy ON

With a stay at this vacation home in Strathroy-Caradoc (Strathroy), you'll be 23.6 mi (37.9 km) from University of Western Ontario and 31.6 mi (50.8 km) from Grand Bend Beach.

Stunning Stay on Dunning Way - Kick back and relax in this calm, stylish space.

St Thomas ON

Located in Saint Thomas, this vacation home is within a 10-minute drive of Pinafore Park and Elgin County Museum.

Adorable Cottage in Port Stanley

Port Stanley ON

$272 nightly

$307 total

May 11 - May 12

Total with taxes and fees

With a stay at this vacation home in Port Stanley, you'll be on the waterfront, within a 5-minute drive of Lake Erie and Port Stanley Terminal Rail.

2026 JUST Released 8 Guest Beach House w/Arcade, Gym, Pool, Yard & pickleball

Port Sranley ON

With a stay at this vacation home, you'll be centrally located in Port Stanley, within a 5-minute drive of Lake Erie and Port Stanley Terminal Rail.

Don't see what you're looking for?

See all available properties in Southwest Middlesex

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.