Southwest Houston Vacation Rentals

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Vacation Rentals in Southwest Houston

Prime Location. Luxurious 3 BR with Pool. 2 Living Rooms. Garage. 4 Balconies.

Houston TX

With a stay at this vacation home, you'll be centrally located in Houston, within a 5-minute drive of Rice University and Westheimer Road.

Pool

Kitchen

🚨Nice 2 bed 2 bath apt near NRG & Med Center 🚨

Houston TX

With a stay at this vacation home in Houston (Texas Medical Center), you'll be within a 5-minute drive of NRG Stadium and MD Anderson Cancer Center.

Pool

Kitchen

Artsy Home, Mins to Bellaire & Galleria, Sleeps 9, Family Friendly

Houston TX

With a stay at this vacation home in Houston (Alief), you'll be within a 15-minute drive of Westheimer Road and CityCentre.

Kitchen

Washer

Exquisite house with loft and great swimming pool

Houston TX

$378 nightly

$435 total

Jan 15 - Jan 16, 2026

Total with taxes and fees

With a stay at this vacation home in Houston (Alief), you'll be a 4-minute drive from Westheimer Road and 7 minutes from CityCentre.

Pool

Hot Tub

Private swimming pool and great house

Houston TX

$308 nightly

$354 total

Dec 16 - Dec 17

Total with taxes and fees

With a stay at this vacation home in Houston (Alief), you'll be a 5-minute drive from Westheimer Road and 8 minutes from CityCentre.

★Signature Retreat★ Prime Location- 15 Min Everywhere

Houston TX

$310 nightly

$357 total

Dec 28 - Dec 29

Total with taxes and fees

With a stay at this vacation home in Houston (Central Southwest), you'll be within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.

Kitchen

Washer

Spacious 4-bedroom house with AC, WiFi, Houston Hideaway 10 min to NRG

Houston TX

With a stay at this vacation home in Houston (Westbury), you'll be within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.

Stunning Modern Dream Home w Pool, Grill, Foosball

Houston TX

With a stay at this vacation home in Houston (Westbury), you'll be within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.

Inviting/Cozy Home in Medical Center - Beautiful home to stay!!

Houston TX

With a stay at this vacation home in Houston (Braeswood Place), you'll be within a 5-minute drive of NRG Stadium and MD Anderson Cancer Center.

Residencia en Houston

Houston TX

$228 nightly

$262 total

Dec 21 - Dec 22

Total with taxes and fees

With a stay at this vacation home in Houston (Central Southwest), you'll be within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.

Washer

Air conditioning

4 Bedroom Home in the center of Galleria/Uptown - 15 min from Downtown

Houston TX

With a stay at this vacation home in Houston (Greater Uptown), you'll be a 1-minute drive from Westheimer Road and 9 minutes from Rice University.

RELAXATION STATION 3-bedroom house in Houston TO RELAX & ENJOY with WiFi, A/C

Houston TX

Located in Houston, this vacation home is within a 15-minute drive of NRG Stadium and MD Anderson Cancer Center.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.