Santa Isabel Vacation Rentals

Get more for your budget and save up to 50% off select Secret Bargain hotels

Get even more value with CheapTickets Price Guarantee!

Change your flight without a fee on select flights

Check dates for Santa Isabel hotels

Vacation Rentals in Santa Isabel

Casa Boni Guest House, Vista única al lago de Carite.

Guayama Guayama

When you stay at this vacation home in Guayama, you'll be on a lake and 12 minutes by car from Bosque Estatal De Carite.

Casa Ponceña Ponce Pueblo

Ponce Puerto Rio

With a stay at this vacation home in Ponce (Ponce Centro), you'll be within a 10-minute drive of La Guancha and Parque de Bombas.

Amazing ViewsMountain topTemp 60s FHeated Spa*

Aibonito PR

When you stay at this vacation home in Aibonito, you'll be in the mountains and 13 minutes by car from Plaza Las Flores.

3-bedroom house in Coamo with AC on bedroom 1

Coamo Pr

$170 nightly

$181 total

Jun 14 - Jun 15

Total with taxes and fees

Located in Coamo, this vacation home is in the mountains, within a 10-minute drive of Coamo Historical Museum and Coamo Springs.

Cielos Panoramic Villas

Naranjito Naranjito

When you stay at this vacation home in Naranjito, you'll be in the mountains and 15 minutes by car from Finca Don Felix para la Naturaleza.

Charming house, stunning views in brilliant Barranquitas with AC, WiFi, Parking

Barranquitas

Located in Barranquitas, this vacation home is in the mountains, within a 15-minute drive of Finca Don Felix para la Naturaleza and San Cristobal Canyon.

Discover the perfect retreat in nature with the best sunset in southern PR.

Salinas Salinas

When you stay at this vacation home in Salinas, you'll be within a 10-minute drive of Marina de Salinas and Albergue Olimpico.

HW Tiny Home Cidra

Cidra Cidra

$177 nightly

$188 total

Jul 7 - Jul 8

Total with taxes and fees

When you stay at this vacation home in Cidra, you'll be 12 minutes by car from Carribbean Cinemas Cayey.

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel

With a stay at this vacation home in Santa Isabel, you'll be within a 10-minute drive of Carribbean Cinemas Santa Isabel and Playa La Ochenta.

Casita La Ley en Cayey with 2-bedroom AC & WiFi.

Cayey Puerto Rico

With a stay at this vacation home in Cayey, you'll be within a 15-minute drive of Carribbean Cinemas Cayey and Bosque Estatal De Carite.

Ponce holiday apartment

Ponce

With a stay at this vacation home, you'll be centrally located in Ponce, within a 5-minute drive of La Guancha and Playa Hilton Ponce.

Boho Style with Private Pool, Cozy 3-bedroom house in beautiful Guayama WiFi, AC

Guayama Guayama

Located in Guayama, this vacation home is in a rural location, a 4-minute drive from Museo Casa Cautino and 6 minutes from Carribbean Cinemas Guayama.

Don't see what you're looking for?

See all available properties in Santa Isabel

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.