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Serena Hotel

Property class: 3

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Photo gallery for Serena Hotel

A hotel entrance with a sign reading "HOTEL SERPENTINE HOTEL."
A hotel room with a large bed, a wooden wardrobe, a desk with a mirror, and a view of buildings through the window.
A lobby with a fire extinguisher, a red trash bin, a framed painting, and a potted plant.
A hotel dining area with round tables covered in yellow tablecloths and red curtains.
A reception desk with a chandelier, multiple wall clocks, and framed documents.

Reviews

7.8 out of 10
Good

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Bar
  • Housekeeping
The current price is $145
$119 nightly
$145 total
Total with taxes and fees
Nov 2 - Nov 3

Explore the area

View in a map
Via Principe Amedeo 64, Rome, RM, 00185
  • Place, Basilica di Santa Maria Maggiore
    ‪3 min walk‬
  • Place, Teatro dell'Opera di Roma
    ‪5 min walk‬
  • Place, Via Nazionale
    ‪6 min walk‬
  • Airport, Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)
    ‪31 min drive‬

Room options

View all photos for Single Room

A hotel room with a bed, a desk with a mirror, and a chair.

Single Room

8.4 out of 10
Very good
(30 reviews)
  • 161 sq ft
  • Sleeps 1
  • 1 Twin Bed

View all photos for Double Room

A hotel room with a bed, a wooden dresser, a chair, and a window with curtains.

Double Room

8.0 out of 10
Very good
(30 reviews)
  • 183 sq ft
  • Sleeps 3
  • 1 Double Bed OR 2 Twin Beds

View all photos for Triple Room

A hotel room with a bed, a wooden dresser, a chair, and a window with curtains.

Triple Room

7.6 out of 10
Good
(5 reviews)
  • 205 sq ft
  • Sleeps 3
  • 3 Twin Beds

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  • Free WiFi
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4.0 out of 5, Very good, 809 reviews
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The price is $107
Nov 15 - Nov 16
Total with taxes and fees
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About the neighborhood

Rome

With a stay at Serena Hotel in Rome (Rome City Centre), you'll be within a 5-minute drive of Colosseum and Villa Borghese. .This hotel is 0.4 mi (0.6 km) from Via Nazionale and 1.3 mi (2 km) from Piazza di Spagna.

What's nearby

  • Piazza Santa Maria Maggiore - 3 min walk - 0.2 miles
  • Basilica di Santa Maria Maggiore - 3 min walk - 0.2 miles
  • Teatro dell'Opera di Roma - 5 min walk - 0.3 miles
  • Piazza della Repubblica - 6 min walk - 0.4 miles
  • Via Nazionale - 6 min walk - 0.4 miles

Getting around

  • Farini Tram Stop - 2 min walk
  • Rome Termini Station - 3 min walk
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 45 min drive

Restaurants

  • ‪McDonald's - ‬2 min walk
  • ‪Aquila Nera - ‬1 min walk
  • ‪Osteria Santa Maria Romana - ‬3 min walk
  • ‪Ristorante Elettra - ‬1 min walk
  • ‪KFC - ‬2 min walk

About this property

Serena Hotel

Serena Hotel offers 50 accommodations with minibars and safes. Flat-screen televisions come with satellite channels. Guests can surf the web using the complimentary wireless Internet access. Housekeeping is provided daily.
Make yourself at home in one of the 50 guestrooms featuring minibars and flat-screen televisions. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Conveniences include safes and desks, and housekeeping is provided daily.
Make use of convenient amenities such as complimentary wireless internet access, tour/ticket assistance, and a reception hall.
Wrap up your day with a drink at the bar/lounge. A complimentary local cuisine breakfast is served daily from 7:30 AM to 10:00 AM.
Featured amenities include express check-in, express check-out, and complimentary newspapers in the lobby.
A complimentary local cuisine breakfast is served each morning between 7:30 AM and 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • No onsite parking available

Food and drink

  • Free local cuisine breakfast available daily 7:30 AM to 10:00 AM
  • A bar/lounge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Luggage storage
  • Safe at front desk

Guest services

  • Housekeeping (daily)
  • Multilingual staff
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)

More

  • 1 building
  • 4 floors
  • Reception hall
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Hair dryer
  • Towels provided

Entertainment

  • Flat-screen TV with satellite channels

Food and drink

  • Minibar

More

  • Air conditioning (climate-controlled)
  • Desk
  • Safe

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: midnight
Express check-in available

Check-out

Check-out before 10:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Guests must contact the property in advance for check-in instructions; front desk staff will greet guests on arrival at the property
To make arrangements for check-in please contact the property ahead of time using the information on the booking confirmation
If you are planning to arrive after midnight please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets stay free
Service animals are welcome, and are exempt from fees
Food and water bowls are available

Children and extra beds

Children are welcome
Children up to the age of 8 years can stay for free if using existing beds when occupying the parent or guardian's room
Cribs (infant beds) are not available

Property payment types

  • American Express
  • Diners Club
  • JCB International
  • Mastercard
  • Visa

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • A tax is imposed by the city: EUR 6.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

We have included all charges provided to us by the property.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit

We should mention

All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation

Property class

This property has received its official star rating from the local rating authority.

Property is also known as

Hotel Serena
Serena Hotel
Serena Hotel Rome
Serena Rome
Serena Hotel Rome
Serena Hotel Hotel
Serena Hotel Hotel Rome

Serena Hotel Reviews

Reviews

7.8

Good

Rating 10 - Excellent. 254 out of 809 reviews
Rating 8 - Good. 321 out of 809 reviews
Rating 6 - Okay. 157 out of 809 reviews
Rating 4 - Poor. 43 out of 809 reviews
Rating 2 - Terrible. 34 out of 809 reviews

8.2/10

Cleanliness

8.4/10

Staff & service

7.6/10

Amenities

7.4/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay!
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a convenient hotel and good service great value for the price
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

I had a very pleasant stay!
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, amenities, property conditions & facilities
Great spot to stay
Stayed 1 night in Dec 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Our breakfast was fresh, good coffee, good service and clean, super close to the train station and shops.
Stayed 3 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy walk from train station. Great location to get around Rome. Staff was friendly. Breakfast was great with a lot of options
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was ver good and the staff freiendly
Stayed 6 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful place to stay while in Rome, rooms are clean and very old fashioned, yet equipment with everything you might need. All the big attractions are close by and easy to walk to or access by bus. And most importantly the staff are super friendly and helpful. I would recommend it and I will definitely stay here again whenever I came back to Rome!
Stayed 3 nights in Jun 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, property conditions & facilities
Disliked: Amenities
Check-in was very quick. The room was comfortable. Close to lots of restaurants.
Stayed 1 night in May 2026
Verified review

6/10 Okay

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location close to the train station.Found room quite small and dark though.Breakfast was just ok.Good for a short stay.
Stayed 2 nights in Jun 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location, great breakfast. The owner is very helpful. Value for money.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It is fun staying at Serena. My wife and I totally enjoyed our stay. Markos is our main man. He is funny and we shared a lot of jokes. Aside from all other staff members are truly tourist oriented. They go all out.
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel conveniently located with a lot of restaurants options
Stayed 1 night in Aug 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Marco was very nice and helpful. Walking distance to Termini station. Great selection of food by the Termini.
Stayed 5 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Great location and staff at the hotel v
Stayed 3 nights in Apr 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel
Stayed 2 nights in Aug 2025
Verified review

6/10 Okay

Liked: Staff & service
clean room, breakfast was Ok and you could walk to major attractions from the hotel; however the area around the hotel was not the greatest specially with kids.
Stayed 4 nights in Apr 2026
Verified review

6/10 Okay

Liked: Cleanliness
Disliked: Amenities
The good - convenient location to Rome Termini station, shops, cafes outside. The not-so-good - AC took forever to cool, staff not so friendly, dark room.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Great staff even during Christmas holidays - easy arrival and checkout and friendly team at work.
Stayed 3 nights in Dec 2025
Verified review

8/10 Good

Liked: Staff & service, property conditions & facilities
Super nice staff and great breakfast!! Very convenient location.
Stayed 3 nights in Oct 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent location and everything was in easy walking distance
Stayed 3 nights in Sep 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great area, clean room, friendly front desk!!
Stayed 1 night in Oct 2025
Verified review

8/10 Good

Liked: Cleanliness
Clean simple room, nice staff.
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Receptionist was very nice, quick check in, room clean, shower big, breakfast super!!! The elevator was a great experience, a travel in time, works perfectly 😊 Cons: A/C was a central unit an is controled by the hotel, it was "on" only for a few hours.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
From the location to the staff- everything was perfect!
Stayed 6 nights in Sep 2025