I stayed at the Grand Hotel Bonanno for a week. It's not smack-dab in the center of Pisa, but it's got its own restaurant and bar. If you wanna shop or eat somewhere else, you gotta walk a bit, which could be rough if you have mobility issues. The staff were always super professional, polite, and friendly. Plus, the breakfast was awesome, with tons of fresh stuff. The only thing that could be better was that they only changed my sheets on the fifth day, after I mentioned that to the chambermaid. It wasn't ideal, considering the hot summer weather.