Mount Pleasant Vacation Rentals

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Vacation Rentals in Mount Pleasant

Private River Getaway with 5 Bedrooms and Pool

Johns Island SC

With a stay at this vacation home in Johns Island, you'll be on the waterfront, and 13.9 mi (22.4 km) from Medical University of South Carolina and 14.6 mi (23.4 km) from College of Charleston.

Pool

Hot Tub

Luxurious 6 Bedroom House Across From Beach! Beach Views, Spa, Pool, Elevator!

Isle of Palms SC

When you stay at this vacation home in Isle of Palms, you'll be near the beach, a 1-minute drive from Front Beach and 8 minutes from Wild Dunes Resort Golf Course.

Pool

Hot Tub

The Overlook on King

Charleston SC

With a stay at this vacation home, you'll be centrally located in Charleston, within a 5-minute drive of College of Charleston and Medical University of South Carolina.

Kitchen

Washer

Location + Luxury 3BD/3BA - 2 Blocks to King!

Charleston SC

$403 nightly

$459 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

A stay at this vacation home places you in the heart of Charleston, within a 10-minute walk of College of Charleston and Medical University of South Carolina.

Kitchen

Washer

Ocean Front Coastal Charm

Folly Beach SC

A stay at this vacation home places you in the heart of Folly Beach, steps from Folly Island Beaches and a 2-minute drive from Folly Beach Fishing Pier.

Kitchen

Washer

Luxury Designer Home, HEATED Pool & Hot Tub, Elevator, Across From Beach Access

Isle of Palms SC

When you stay at this vacation home in Isle of Palms, you'll be near the beach, within a 15-minute drive of Front Beach and Wild Dunes Resort Golf Course.

Pool

Hot Tub

Oceanfront Home w/ Private Pool, Roof Deck, Porches & Game Room -- Incredible Ocean & Marsh Views

Folly Beach SC

With a stay at this vacation home in Folly Beach, you'll be on the beach, just a 2-minute walk from Folly Island Beaches and 9 minutes by foot from Lighthouse Inlet Heritage Preserve.

Pool

Kitchen

Entire 4 Bedroom Historic Charleston House

Charleston SC

A stay at this vacation home places you in the heart of Charleston, within a 15-minute walk of Medical University of South Carolina and College of Charleston.

Kitchen

Washer

Luxury Townhouse near Downtown and Beaches with Hot Tub

Mount Pleasant SC

$286 nightly

$323 total

Dec 7 - Dec 8

Total with taxes and fees

With a stay at this vacation home in Mount Pleasant, you'll be within a 10-minute drive of Patriots Point and College of Charleston.

Hot Tub

Kitchen

Charming 4-bedroom house near Park Circle in North Charleston

North Charleston SC

$441 nightly

$503 total

Dec 27 - Dec 28

Total with taxes and fees

With a stay at this vacation home in North Charleston, you'll be within a 15-minute drive of North Charleston Coliseum and Performing Arts Center and College of Charleston.

Washer

Dryer

Enjoy Charlestons History & Carolina Sun - 3BR 2 BATH Old Mt. Pleasant

Mt Pleasant SC

With a stay at this vacation home in Mount Pleasant (Old Village), you'll be within a 10-minute drive of Patriots Point and Front Beach.

Kitchen

Washer

Shem Creek Corner, one block from Historic Shem Creek waterway, beaches close

Mt Pleasant SC

With a stay at this vacation home in Mount Pleasant (Old Village), you'll be within a 10-minute drive of Patriots Point and South Carolina Aquarium.

Kitchen

Washer

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.