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21c Museum Hotel Louisville

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Photo gallery for 21c Museum Hotel Louisville

A classical gold statue in front of a multi-story building with large windows and a brick facade.
A steam fountain in a brick alleyway.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Spa
  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Gym
The current price is $216
$183 nightly
$216 total
Total with taxes and fees
Aug 22 - Aug 23

Explore the area

View in a map
700 W Main Street, Louisville, KY, 40202
  • Place, 21c Museum Hotel
    ‪1 min walk‬
  • Place, Muhammad Ali Center
    ‪3 min walk‬
  • Place, Louisville Slugger Museum
    ‪3 min walk‬
  • Airport, Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

Room options

View all photos for Deluxe Double Room, 2 Double Beds

A hotel room with two beds, a headboard with a framed artwork of birds, a bedside table with a lamp, and a small bookshelf.

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(34 reviews)
  • 335 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free WiFi

View all photos for Luxury Double Room, 2 Double Beds

A hotel room with two beds, a desk, a chair, a lamp, and a large window with a view.

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 435 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free WiFi

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(78 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Luxury Room, 1 King Bed

A hotel room with a large bed, a chair, a desk, and a window with curtains.

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(36 reviews)
  • City view
  • 455 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Suite, Corner

A modern living room with a grey sofa, a red decorative piece, a white armchair, and a dining area with a table and chairs.

Suite, Corner

  • City view
  • 660 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Room (Asleep in the Cyclone)

A room with a geometric-patterned ceiling, a bed with a patterned bedspread, and a nightstand with a lamp.

Room (Asleep in the Cyclone)

  • 500 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Suite (Atrium)

A hotel room with a bed, desk, chair, dresser, and a sofa.

Suite (Atrium)

  • 580 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Room, Balcony

A hotel room with a large bed, a nightstand with a lamp, a chair, and a view of the outdoors.

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • City view
  • 315 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Double Room, Accessible

A modern bathroom with a white sink, mirror, and toilet.

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 455 sq ft
  • Sleeps 4
  • 2 Double Beds
  • Free WiFi

View all photos for Deluxe Room, 1 King Bed, Accessible

A hotel room with a large bed, two bedside tables with lamps, a wooden headboard, a large mirror, and a wall-mounted abstract art piece.

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(2 reviews)
  • 434 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Room, 1 King Bed, Accessible

A hotel room with a large bed, two bedside tables with lamps, a wooden headboard, a large mirror, and a wall-mounted abstract art piece.

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 435 sq ft
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Apartment, 1 Double Bed (Rooftop)

A modern interior with a dining area, a patterned bench, and a large window with a city view.

Apartment, 1 Double Bed (Rooftop)

10.0 out of 10
Exceptional
(1 review)
  • City view
  • Sleeps 4
  • 1 Double Bed
  • Free WiFi

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Total with taxes and fees
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About the neighborhood

Louisville

With a stay at 21c Museum Hotel Louisville, you'll be centrally located in Louisville, steps from Louisville Slugger Museum and 8 minutes by foot from Kentucky International Convention Center. .This luxury hotel is 0.4 mi (0.7 km) from KFC Yum Center and 6.8 mi (10.9 km) from Kentucky Exposition Center.

What's nearby

  • 21c Museum Hotel - 1 min walk - 0.1 miles
  • Muhammad Ali Center - 3 min walk - 0.2 miles
  • Louisville Slugger Museum - 3 min walk - 0.2 miles
  • Kentucky Bourbon Trail Visitor Center - 5 min walk - 0.3 miles
  • Kentucky International Convention Center - 8 min walk - 0.5 miles

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪McDonald's - ‬3 min drive
  • ‪The Old Spaghetti Factory - ‬9 min walk
  • ‪Indi's Fast Food Restaurant - ‬2 min drive
  • ‪Humana Waterside Building - ‬11 min walk
  • ‪White Castle - ‬16 min walk

About this property

21c Museum Hotel Louisville

21c Museum Hotel Louisville offers 91 accommodations with minibars and laptop-compatible safes. Beds feature down comforters and premium bedding. 50-inch LCD televisions come with premium cable channels. Bathrooms include bathrobes, designer toiletries, complimentary toiletries, and hair dryers.

This Louisville hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Additionally, rooms include espresso makers and complimentary bottled water. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages, and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.
Make yourself at home in one of the 91 guestrooms featuring minibars and espresso makers. Your bed comes with down comforters and premium bedding. Wired and wireless internet access is complimentary, while 50-inch LCD televisions with cable programming provide entertainment. Private bathrooms have designer toiletries and hair dryers.
Relax at the full-service spa, where you can enjoy massages. Additional features at this hotel include complimentary wireless internet access, concierge services, and gift shops/newsstands.
Grab a bite to eat at Proof on Main, a fine-dining restaurant which features a bar/lounge, or stay in and take advantage of the room service (during limited hours). Full breakfasts are served on weekdays from 7:00 AM to 10:00 AM and on weekends from 8:00 AM to 1:00 PM for a fee.
Featured amenities include complimentary wired internet access, a 24-hour business center, and limo/town car service. Planning an event in Louisville? This hotel has 5000 square feet (465 square meters) of space consisting of conference space and meeting rooms.
Full breakfasts are available for a surcharge on weekdays between 7:00 AM and 10:00 AM and on weekends between 8:00 AM and 1:00 PM.
Proof on Main - This fine-dining restaurant serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar. Open daily.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Wheelchair-accessible parking available

Food and drink

  • Full breakfast available for a fee 7:00 AM to 10:00 AM on weekdays and 8:00 AM to 1:00 PM on weekends; USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room crib
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance

Business services

  • 24-hour business center
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • Deep-tissue massages
  • Hot stone massages
  • In-room massages
  • Prenatal massages
  • Sauna
  • Spa open daily
  • Sports massages
  • Steam room
  • Swedish massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Built in 2006
  • Comprehensive food waste policy
  • Double-glazed windows
  • Eco-friendly cleaning products used
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Non-plastic coffee stirrers available
  • Non-plastic drinking straws available
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed
  • Some LED lighting used
  • Vegan dining options

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free crib
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathrobes
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • iPod dock

Food and drink

  • Champagne service
  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 40.00 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Up to 50 lbs per pet
Food and water bowls are available

Children and extra beds

Children are welcome
Rollaway/extra beds are available for USD 30.0 per night
Free cribs are available on request at the property

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5.00 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
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Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
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21c Museum Hotel Louisville Louisville
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21c Museum Hotel Louisville Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 788 out of 1008 reviews
Rating 8 - Good. 123 out of 1008 reviews
Rating 6 - Okay. 59 out of 1008 reviews
Rating 4 - Poor. 20 out of 1008 reviews
Rating 2 - Terrible. 18 out of 1008 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Catherine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Located downtown next to all the great places to visit and eat. You can't go wrong staying here, the staff is wonderful and the food is great.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Kristin Woxland

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely hotel. Would stay there again.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Brent

Liked: Cleanliness, amenities, property conditions & facilities
Nice room and close to all the distilleries. Great restaurant on site as well!
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Meredith

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Jason

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town.
Stayed 1 night in Apr 2026
Verified review

6/10 Okay

Laurie Beth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was wonderful - unfortunately our vehicle was broken into in the parking garage but the hotel staff helped us clean up the glass and cover the window and took a report. Bar staff was super fun and friendly and loved the overall vibe.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Salvatore

Liked: Cleanliness, amenities, property conditions & facilities
Clean hotel…very cool vibe!!!
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Julie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The menu at the lically-sourced farm to table restaurant is inventive and incredibly delicious. Ramps, local mushrooms, hand-pulled pastas. The prices are extremely fair for this quality of meal.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Madeline

Liked: Cleanliness, amenities, property conditions & facilities
Location and the staff was fabulous.
Stayed 2 nights in Jan 2026
Verified review

10/10 Excellent

Dean

Liked: Cleanliness, staff & service, amenities
Great room and amenities.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

KARI

Liked: Cleanliness, staff & service, property conditions & facilities
The stay was amzn!!!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Amanada

Liked: Cleanliness, amenities, property conditions & facilities
Large spacious room and super comfortable bed Fascinating art and super bar and restaurant too Great service from all staff
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Carter

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and quiet room
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Elizabeth

Liked: Cleanliness, staff & service, amenities
The staff was super friendly
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

pamela

Liked: Cleanliness, property conditions & facilities
Lovely comfortable place to stay !
Stayed 1 night in Nov 2025
Verified review

10/10 Excellent

Tamara

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21C is by far the best hotel we’ve ever stayed in. The museum is fantastic! The entire Staff went above and beyond for us.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

MARC

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The rooms and staff were great and the penguins were alive.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Rachel

Liked: Cleanliness, amenities, property conditions & facilities
Great room, super kind staff
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff and a wonderful lobby experience. Room was spacious and clean. Restaurant and bar were both very good.
Stayed 3 nights in Mar 2026
Verified review

10/10 Excellent

Holly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21c in Louisville is always awesome. The property is well appointed and attractive. The staff is friendly, helpful and welcoming. The food is first rate and there is always so much to look at. It’s my favorite hotel in Louisville.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Karen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Fun hotel, lots of interesting art, very comfortable, excellent staff
Stayed 2 nights in Jan 2026
Verified review

10/10 Excellent

Joshua

Liked: Cleanliness, property conditions & facilities
This was an amazing hotel! Loved all the art and the bed was super comfortable. Hope to return one day!
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Casey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really cool place, great location. Very glad we chose this one. Would definitely recommend.
Stayed 3 nights in Mar 2026
Verified review

10/10 Excellent

Anatole

Liked: Cleanliness, amenities, property conditions & facilities
Excellent place.
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Erica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved our stay, would definitely plan to come back if we are ever in the area again.
Stayed 1 night in Oct 2025