See all properties

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

2.5 star property

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.
A spacious lobby with a central seating area, a reception desk, and a bar.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
A modern lobby with seating areas, a reception desk, and a view of the outside.
A Holiday Inn Express & Suites building with a modern design, featuring a prominent entrance with a covered walkway and large windows.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
The current price is $139
$119 nightly
$139 total
Total with taxes and fees
Aug 17 - Aug 18

Explore the area

View in a map
9300 S Main Street, Houston, TX, 77025
  • Place, NRG Park
    ‪3 min walk‬
  • Place, NRG Stadium
    ‪17 min walk‬
  • Place, NRG Center
    ‪20 min walk‬
  • Airport, Houston, TX (IAH-George Bush Intercontinental)
    ‪35 min drive‬

Room options

View all photos for Standard Room

A bed with white bedding and pillows against a wooden headboard.

Standard Room

9.4 out of 10
Exceptional
(24 reviews)
  • 323 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Standard Room, 1 King Bed

A hotel room with a large bed, a desk with a TV, a chair, a desk lamp, and a window with curtains.

Standard Room, 1 King Bed

9.6 out of 10
Exceptional
(114 reviews)
  • 325 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds

A hotel room with two beds, a desk with a TV, a chair, a lamp, and a window with curtains.

Standard Room, 2 Queen Beds

9.2 out of 10
Wonderful
(63 reviews)
  • 325 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 2 Queen Beds

A hotel room with two beds, a desk with a TV, a chair, and a small table.

Suite, 2 Queen Beds

8.8 out of 10
Excellent
(20 reviews)
  • 377 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

Suite, 1 King Bed

9.8 out of 10
Exceptional
(6 reviews)
  • 375 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Roll-in Shower (Communications)

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

Suite, 1 King Bed, Roll-in Shower (Communications)

10.0 out of 10
Exceptional
(1 review)
  • 375 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Accessible (Communications)

A hotel room with a blue sofa, a wooden nightstand with a lamp, a bed, and a window with curtains.

Suite, 2 Queen Beds, Accessible (Communications)

9.2 out of 10
Wonderful
(5 reviews)
  • 375 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Accessible Bathtub (Communications)

A hotel room with two beds, a desk with a TV, a chair, and a small table.

Standard Room, 2 Queen Beds, Accessible Bathtub (Communications)

9.6 out of 10
Exceptional
(19 reviews)
  • 350 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible (Communications)

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

Suite, 1 King Bed, Accessible (Communications)

10.0 out of 10
Exceptional
(2 reviews)
  • 375 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 2 Queen Beds, Accessible Bathtub (Communications)

A hotel room with two beds, a desk with a lamp, a TV, and a chair.

Suite, 2 Queen Beds, Accessible Bathtub (Communications)

9.8 out of 10
Exceptional
(6 reviews)
  • 375 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Accessible (Communications)

A hotel room with a large bed, a desk with a TV, a chair, a desk lamp, and a window with curtains.

Standard Room, 1 King Bed, Accessible (Communications)

10.0 out of 10
Exceptional
(7 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Standard Room, 2 Queen Beds, Accessible (Communications)

A hotel room with two beds, a desk with a TV, a chair, a lamp, and a window with curtains.

Standard Room, 2 Queen Beds, Accessible (Communications)

8.0 out of 10
Very good
(1 review)
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Standard Room, 1 King Bed, Roll-in Shower (Communications)

A hotel room with a large bed, a desk with a TV, a chair, a desk lamp, and a window with curtains.

Standard Room, 1 King Bed, Roll-in Shower (Communications)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Room (Specialty)

A hotel room with a bed, a desk with a chair, a TV, a bedside table with a lamp, and a small seating area.

Room (Specialty)

  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bed
  • Free WiFi

Similar properties

Exterior
Home2 Suites by Hilton at the Galleria
Greater Uptown
  • Pool
  • Breakfast included
  • Pet friendly
  • Free WiFi
4.5 out of 5, Wonderful, 1,029 reviews
$106 nightly
The price is $124
Aug 16 - Aug 17
Total with taxes and fees
Home2 Suites by Hilton at the Galleria

About the neighborhood

Houston

With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from NRG Park and 14 minutes by foot from NRG Stadium. .This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.

What's nearby

  • NRG Park - 3 min walk - 0.2 miles
  • NRG Stadium - 17 min walk - 0.9 miles
  • NRG Center - 20 min walk - 1.1 miles
  • NRG Arena - 4 min drive - 2.1 miles
  • NRG Astrodome - 5 min drive - 1.2 miles

Getting around

  • Smith Lands Station - 3 min drive
  • Kinder Station - 7 min drive
  • Houston William Hobby Airport (HOU) - 28 min drive

Restaurants

  • ‪McDonald's - ‬10 min walk
  • ‪Raising Cane's Chicken Fingers - ‬6 min walk
  • ‪Whataburger - ‬13 min walk
  • ‪Slim Chickens - ‬7 min walk
  • ‪Pappas Bar-B-Q - ‬12 min walk

About this property

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG offers 146 air-conditioned accommodations with safes and coffee/tea makers. LCD televisions come with premium cable channels. Refrigerators and microwaves are provided. Bathrooms include shower/tub combinations and hair dryers.

This Houston hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Recreational amenities at the hotel include an outdoor pool and a 24-hour fitness center.
Make yourself at home in one of the 146 air-conditioned rooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature hair dryers and toothbrushes and toothpaste. Conveniences include safes and desks, as well as phones with free local calls.
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a banquet hall.
A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:30 AM and on weekends from 6:30 AM to 10:00 AM.
Featured amenities include a 24-hour business center, express check-in, and express check-out. Planning an event in Houston? This hotel has 675 square feet (63 square meters) of space consisting of conference space and 2 meeting rooms. Free self parking is available onsite.
A complimentary continental breakfast is served on weekdays between 6:00 AM and 9:30 AM and on weekends between 6:30 AM and 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible van parking available
  • Onsite parking includes off-street options

Food and drink

  • Free continental breakfast available 6:00 AM to 9:30 AM on weekdays and 6:30 AM to 10:00 AM on weekends

Things to do

  • 24-hour gym
  • Outdoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff

Business services

  • 2 meeting rooms
  • 24-hour business center
  • 675 square feet of conference space

Outdoors

  • Outdoor furniture
  • Pool loungers
  • Pool umbrellas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Braille/raised signage
  • Grab bar near toilet
  • Handrails in stairways
  • Pool hoist on site
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 4 floors
  • Banquet hall
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Hair dryer
  • Private bathroom
  • Shampoo
  • Shower/bathtub combination
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • LCD TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in time starts at 3 PM
Early check-in subject to availability
Early check-in is available for a fee
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Destination fee: USD 0.81 per accommodation, per night

We have included all charges provided to us by the property.

Optional extras

  • Early check-in is available for a fee (subject to availability)
  • Late check-out is available for a fee (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 10 AM to 10 PM
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Houston SW Medical Ctr Area Hotel
Holiday Inn Express SW Medical Ctr Area Hotel
Holiday Inn Express Houston SW Medical Ctr Area
Holiday Inn Express SW Medical Ctr Area
Holiday Inn Express Houston
Holiday Inn Express Suites Houston Medical Center
Holiday Inn Express Suites Houston S Medical Ctr Area
Holiday Inn Express Suites Houston S Medical Ctr Area by IHG
Holiday Inn Express Suites Houston Medical Center an IHG Hotel

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 790 out of 1007 reviews
Rating 8 - Good. 141 out of 1007 reviews
Rating 6 - Okay. 31 out of 1007 reviews
Rating 4 - Poor. 15 out of 1007 reviews
Rating 2 - Terrible. 30 out of 1007 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Lini Jay

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice place to stay. Clean, convenient and friendly staff
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Nina

Liked: Cleanliness, staff & service, property conditions & facilities
My stay was very pleasant, courtesy staff, clean and comfortable rooms and breakfast was great
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Julie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy Check in, friendly staff, room was clean, breakfast was good - would stay here again.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Pechie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice stay would recommend to anyone, very close to the stadium
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Judith

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
yes the breakfast was great
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The biscuits and gravy were delicious and definitely worth the trip!!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Steve

Liked: Cleanliness
Breakfast was good parking safe
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Juan M

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fresh breakfast every morning, rooms were clean, & parking had a security guard every night on site.
Stayed 3 nights in Apr 2026
Verified review

10/10 Excellent

Michele

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and great location
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Tammy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
They have a very good breakfast. Very clean rooms, and the Staff was helpful when we needed something. Check-in was easy and the Staff was very accommodating.
Stayed 2 nights in Apr 2026
Verified review

8/10 Good

KAAN ORCUN

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel is decent; clean and convenient, staff is super nice, parking is safe, lots of fast food places around
Stayed 5 nights in Mar 2026
Verified review

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean facility with friendly!
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Paul

Liked: Cleanliness, staff & service, amenities
Staff was helpful and courteous, room was clean, breakfast was nice. My family and I enjoyed our stay.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Kyle

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Parking was accessible, safe and well-maintained property.
Stayed 2 nights in Apr 2026
Verified review

8/10 Good

Joan

Liked: Cleanliness, amenities, property conditions & facilities
Clean, well run hotel and great location.
Stayed 4 nights in Nov 2025
Verified review

10/10 Excellent

Paul

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, customer service was excellent and breakfast was great and plenty. Also great location
Stayed 4 nights in Feb 2026
Verified review

10/10 Excellent

Ruth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location. Nice rooms. Breakfast was good.
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Vicki

Staff very nice & room was nice and clean.
Stayed 4 nights in Jan 2026
Verified review

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly; breakfast attendant worked diligently to ensure everyone was taken care of. Beds were comfy!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities
Very clean rooms great front desk staff I will stay again if needed excellent maintenance staff as well
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Sherrilynne

Liked: Cleanliness, staff & service, property conditions & facilities
The room was nice and clean. Staff professional and friendly
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Nayela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay
Stayed 1 night in Aug 2025
Verified review

10/10 Excellent

Jason

Liked: Cleanliness, staff & service, amenities
Great stay. Staff was attentive and accommodating. Room was clean. Enjoyed our stay.
Stayed 1 night in Feb 2026
Verified review

8/10 Good

Daniel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice hotel, clean, good WiFi and good breakfast room. A slow check in as there was only one staff member and many guests.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The gym was equipped well. The staff was very friendly. Hotel rooms were clean and comfortable. We would stay there again.
Stayed 1 night in Mar 2026

Top Picks