Important: This destination may have COVID-19 travel restrictions in place, including specific restrictions for lodging. Check any national, local, and health advisories for this destination before you book.

Cheap flights from Myrtle Beach (MYR) to Knoxville (TYS)

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Lowest round trip fares by airline from Myrtle Beach and Knoxville

Cheapest prices ($86 One Way, $154 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Great Deals On Cheap Hotels in Knoxville

Motel 6 Knoxville, TN

Motel 6 Knoxville, TN

2 out of 5
258 Harry Lane Blvd, Knoxville, TN
The price is $60 per night from Aug 8 to Aug 8
Situated in Knoxville, this motel is 2.5 mi (4 km) from Dead Horse Lake Golf Course and within 6 mi (10 km) of West Town Mall and Turkey Creek Shopping Center. ...
2.6/5 (5 reviews)
I wish I could get a voucher or my money back!
"The only bright spot about the entire trip was Rebecca the desk clerk. The rest was horrible. Between the loud slamming of doors, people screaming, arguing at all hours of night up into the light of day, I was miserable."

Reviewed on Jul 29, 2018

Motel 6 Knoxville, TN
Red Roof Inn Knoxville Central - Papermill Road

Red Roof Inn Knoxville Central - Papermill Road

2 out of 5
1315 Kirby Rd, Knoxville, TN
The price is $60 per night from Aug 19 to Aug 19
Situated near the airport, this hotel is 1.9 mi (3.1 km) from Bearden Antique Mall and 2.8 mi (4.4 km) from West Town Mall. Tennessee River is 2.4 mi (3.9 km) ...
Red Roof Inn Knoxville Central - Papermill Road
Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff

Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff

2.5 out of 5
208 Market Pl Blvd, Knoxville, TN
The price is $87 per night from Aug 9 to Aug 9
Situated in the suburbs, this motel is within 9 mi (15 km) of West Town Mall, Pellissippi State Community College, and Willow Creek Golf Club. Knoxville Museum ...
Red Roof Inn PLUS+ & Suites Knoxville West – Cedar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fly From Myrtle Beach to Knoxville

Origin Myrtle Beach
Destination Knoxville
Number of Daily Flights
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Myrtle Beach to Knoxville

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.