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Lowest round trip fares by airline from San Diego County and Charleston

Cheapest prices ($165 One Way, $327 Round Trip) found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fly From San Diego County to Charleston

OriginSan Diego County
DestinationCharleston
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Cheap flights from San Diego County to Charleston

Cheap flights from San Diego County to Charleston

Are you ready to book your flight, but feeling nervous about paying too much if the price drops? Don't play the waiting game. Our Best Price Guarantee means if you see a better fare for the same flight, we'll give you the difference in CheapCash, plus a $50 CheapCash bonus, which you can use to save on your hotel reservation.

If you have a frequent flier account, add it to your reservation to earn miles. And don't worry about getting stuck in a middle seat. Choose your seats when you book, so you'll be right where you want to be on departure day.

Save Even More Time and Money With a Charleston Travel Package

Once your flights are booked, why start all over again searching for a cheap hotel? Book your flight and hotel together, and save yourself more than time and energy. You'll also be able to take advantage of discounts and coupons on your Charleston vacation that you can't get when you book flights and hotel separately.

Relax in Charleston With Confidence and Convenience

Going cheap doesn't mean giving up great service. Our agents are available 24/7 to help you find the right cheap flights and hotel, and to answer questions about your trip.

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Hotels in Charleston

See all 2,214 Properties in Charleston
Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

560 King Street, Charleston, SC
    3.5 out of 5.0
     
     
    4.4 out of 5 (7 reviews)

    Located in Downtown Charleston, this hotel is within a 10-minute walk of PURE Theatre and Charleston Music Hall. College of Charleston and Medical University ...

    Hyatt Place Charleston/Historic District$174

    Hyatt Place Charleston/Historic District$174
    The Francis Marion Hotel

    The Francis Marion Hotel

    387 King St, Charleston, SC
      4.0 out of 5.0
       
       
      4.1 out of 5 (31 reviews)

      Located in Charleston Historic District, this spa hotel is steps from Marion Square and College of Charleston. Charleston Music Hall and Charleston Museum are ...

      The Francis Marion Hotel$149

      The Francis Marion Hotel$149
      Wingate By Wyndham Charleston

      Wingate By Wyndham Charleston

      9280 University Blvd, North Charleston, SC
        2.5 out of 5.0
         
         
        4.7 out of 5 (7 reviews)

        Situated in North Charleston, this hotel is within 1 mi (2 km) of Charleston Southern University and Whirlin' Waters Adventure Waterpark. Wannamaker County Park ...

        Wingate By Wyndham Charleston$87

        Wingate By Wyndham Charleston$87
        Holiday Inn Express Charleston Dwtn - Medical Area

        Holiday Inn Express Charleston Dwtn - Medical Area

        250 Spring Street, Charleston, SC
          3.0 out of 5.0
           
           
          4.3 out of 5 (3 reviews)

          Located in Downtown Charleston, this hotel is within 1 mi (2 km) of Joseph P. Riley, Jr. Park, Medical University of South Carolina, and The Citadel. College ...

          Holiday Inn Express Charleston Dwtn - Medical Area$84

          Holiday Inn Express Charleston Dwtn - Medical Area$84
          The Meeting Street Inn

          The Meeting Street Inn

          173 Meeting Street, Charleston, SC
            3.0 out of 5.0
             
             
            3.7 out of 5 (3 reviews)

            Located in Charleston Historic District, this hotel is steps from Confederate Museum and Charleston City Market. Port of Charleston Cruise Terminal and Waterfront ...

            The Meeting Street Inn$143

            The Meeting Street Inn$143
            Harborside at Charleston Harbor Resort and Marina

            Harborside at Charleston Harbor Resort and Marina

            20 Patriots Point Rd, Mount Pleasant, SC
              4.0 out of 5.0
               
               
              3.9 out of 5 (32 reviews)

              Situated in Mount Pleasant, this beach resort is within a 5-minute walk of Patriots Point and USS Yorktown. Patriots Point Naval and Maritime Museum and Patriots ...

              Harborside at Charleston Harbor Resort and Marina$119

              Harborside at Charleston Harbor Resort and Marina$119
              King Charles Inn

              King Charles Inn

              237 Meeting Street, Charleston, SC
                3.5 out of 5.0
                 
                 
                4.4 out of 5 (14 reviews)

                Located in Charleston Historic District, this hotel is within a 5-minute walk of St. Mary's Roman Catholic Church and Charleston City Market. Port of Charleston ...

                King Charles Inn$159

                King Charles Inn$159
                The Mills House Wyndham Grand Hotel

                The Mills House Wyndham Grand Hotel

                115 Meeting Street, Charleston, SC
                  4.0 out of 5.0
                   
                   
                  4.2 out of 5 (10 reviews)

                  Located in Charleston Historic District, this romantic hotel is within a 5-minute walk of Gibbes Museum of Art and Charleston City Market. Waterfront Park and ...

                  The Mills House Wyndham Grand Hotel$169

                  The Mills House Wyndham Grand Hotel$169
                  Tides Folly Beach Hotel

                  Tides Folly Beach Hotel

                  1 Center Street Highway 171, Folly Beach, SC
                    3.0 out of 5.0
                     
                     
                    4.0 out of 5 (8 reviews)

                    Located in Folly Beach, this beachfront hotel is in the entertainment district and within a 5-minute walk of Folly Beach and Folly Beach Fishing Pier. Folly ...

                    Tides Folly Beach Hotel$119

                    Tides Folly Beach Hotel$119
                    Hyatt House Charleston/Historic District

                    Hyatt House Charleston/Historic District

                    560 King Street, Charleston, SC
                      3.0 out of 5.0
                       
                       
                      5.0 out of 5 (2 reviews)

                      Located in Downtown Charleston, this hotel is within a 10-minute walk of PURE Theatre and Charleston Music Hall. College of Charleston and Medical University ...

                      Hyatt House Charleston/Historic District$183

                      Hyatt House Charleston/Historic District$183
                      Map

                      *Savings based on all holiday package bookings with Flight + Hotel on CheapTickets.com from January through December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

                      *Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.