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Cheap flights from Houston (HOU) to San Francisco (QSF)

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Lowest round trip fares by airline from Houston and San Francisco

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Cheap flights from Houston to San Francisco

Cheap flights from Houston to San Francisco

Houston George Bush Intercontinental (IAH) is located 23 miles north of downtown Houston, and is easily accessible via Interstate Route 45 and Highway 59. Flights from Houston to San Francisco International Airport (SFO) take 4 to 5 hours, and once in San Francisco, the Bay Area Rapid Transit offers connections to many nearby destinations.

Also available for transportation are the Caltrain commuter rail and SamTrans bus routes, as well as car rentals, taxis and limos.

Attractions and tips

Everyone visiting San Francisco stops to see the famous Golden Gate Bridge, which spans 1.7 miles, and Fisherman’s Wharf is well known for its vendors of crab, clam chowder and sourdough bread bowls.

You’ll also be able to see Alcatraz Island, once the home of a federal prison which was in operation from 1933 – 1963. Visitors can also visit the island itself, which is managed by the National Park Service and is home to rare plants and birdlife. The island also boasts the ruins of the prison and visitors can learn about the history of the island, including the Native American occupation of Alcatraz, which ran from 1964-1971.

San Francisco is home to the National Football League’s San Francisco 49’ers, who play at Candlestick Park, and Major League Baseball’s San Francisco Giants, who play at SBC Park. Numerous water sports and boating and sailing are available to visitors who wish to take advantage of the city’s seaside location.

Packages from Houston to San Francisco

Hotels in San Francisco

See all 491 Hotels in San Francisco
Villa Florence

Villa Florence

225 Powell St, San Francisco
4.0 out of 5.0
4.2 out of 5 (11 reviews)

Infused with the spirit of Italy, this romantic downtown San Francisco retreat is on the Powell Street cable car line, less than a block from Union Square; theaters ...

$140

$140
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.2 out of 5 (20 reviews)

Built around a skylit open atrium, this fully renovated 9-story hotel on San Francisco Bay features an onsite restaurant and is located 2.5 miles from the airport, ...

$139

$139
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (23 reviews)

Located in North Beach, this hotel is within a 10-minute walk of Ripley's Believe It Or Not Museum, Wax Museum at Fisherman's Wharf, and Ghirardelli Square. ...

$246

$246
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
3.9 out of 5 (26 reviews)

Rising 36 stories above Union Square, this sleek, contemporary hotel is 1 block from cable cars, 3 blocks from Westfield San Francisco Centre shopping mall, ...

$189

$189
Travelodge San Francisco Airport-North

Travelodge San Francisco Airport-North

326 S Airport Blvd, South San Francisco
2.0 out of 5.0
2.7 out of 5 (72 reviews)

This 200-room hotel is 2 miles north of San Francisco International Airport and 10 miles from downtown San Francisco.

$93

$93
Sweden House Hotel

Sweden House Hotel

570 O'farrell St, San Francisco
2.5 out of 5.0
1.2 out of 5 (4 reviews)

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Bohemian Club, Union Square, and Westfield San Francisco Centre. Asian Art Museum ...

$76

$76
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
4.0 out of 5 (52 reviews)

A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the San Francisco Museum of Modern ...

$169

$169
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.4 out of 5 (7 reviews)

The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks from the Powell Street cable car.

$168

$168
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
4.0 out of 5 (48 reviews)

Iconic, AAA 4-Diamond hotel a few steps from Union Square, Cable Car station, theatre district, BART, Chinatown, SFMOMA, and Moscone Center. Upgraded rooms offer ...

$179

$179
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.5 out of 5 (79 reviews)

Located in the San Francisco theater district with a BART and MUNI station at its entrance, this downtown hotel is 6 blocks from Union Square and within a mile ...

$135

$135
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other CheapTickets users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $75 service fee charged by CheapTickets.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.